What Medications Are Used During Ovulation Stimulation
Letrozole is a drug used to stimulate ovulation in anovulatory infertility, or to obtain several follicles during ovulatory cycles. Femara is also prescribed for various disorders of the menstrual cycle. Femara is an antiestrogenic drug that lowers estrogen levels in the blood, resulting in the body producing large amounts of FSH, which acts on the ovaries and leads to the formation of one or more follicles. Approximately 30% of women who do not ovulate after receiving clostilbegit tend to ovulate after taking Femara. The drug is taken 1 or 2 tablets a day, at the same time of day for 5 days, starting with 3, 4 or 5 days of the menstrual cycle.
Side effects of Letrozole
Although many women do not complain of taking Femara, some may still experience bone pain, hot flashes, upset stomach, joint pain, fatigue, dizziness, cough, headache, and insomnia. Usually after taking only 5 Femara tablets, such side effects do not occur, but if they are present, you should immediately consult your doctor. After taking Femara, the chances of pregnancy increase, and in 5-8% of cases it can be double if more than one follicle was obtained during the stimulation period. Triplets are very rare (less than 1%). There has been no increase in miscarriages, stillbirths or fetal malformations after taking Femara. There is also no increase in the risk of ovarian or breast cancer.
It is a drug that is used to stimulate ovulation in women with anovulatory infertility, or to produce multiple follicles in women with ovulatory cycles. Clostilbegit directly blocks estrogen receptors, which leads to lower estrogen levels in the blood. This in turn leads to increased production of FSH in the pituitary gland. FSH affects the ovaries, in which follicles (one or more) begin to grow. The dose of clostilbegit is selected by the doctor, depending on the specific situation.
How to Take Clomiphene Citrate?
The patient should take the drug at the same time of day, starting with 3,4 or 5 days of the menstrual cycle for 5 days. However, medical pills require ultrasound to determine the level of certain hormones in the blood before starting clostilbegit stimulation. In cases where FSH and E2 levels are elevated on day 3 of the menstrual cycle, or there are residual cysts 2 cm or more in diameter, clostilbegit should not be prescribed. In 5 days after taking the drug it is necessary to conduct ultrasound and some blood tests, which makes it possible to assess the body’s response to stimulation, ie. how many dominant follicles are there and what is the thickness of the endometrium.
Gonadotropins are ovulation stimulants that are injected. These include pure gonadotropins containing only FSH (Gonal-F, Puregon, Follitropin, etc.), as well as human menopausal gonadotropins, which include FSH and LH (Menotropin, Menopur, Menogon, etc.). . These drugs are prescribed for anovulatory infertility in order to achieve ovulation, as well as to increase the chances of pregnancy in the case of ovulatory cycles, ie. after the appointment of gonadotropins, a larger number of follicles mature with the corresponding follicles inside them. In addition, gonadotropins are used to produce many follicles in preparation for the IVF program. Ultrasound and some hormonal tests should be performed before prescribing gonadotropins to rule out residual ovarian cysts. At high levels of FSH and E2, stimulation should be discontinued. After receiving gonadotropin injections, you need to have an ultrasound and some blood tests. Every woman responds differently to stimulation. Usually ultrasound is performed 4 days after receiving the injections, and then even more often, perhaps even every day until the follicle reaches 18 mm. Next, an injection of chorionic gonadotropin is prescribed, after which ovulation is known to occur after 36-40 hours. And during this time, either intrauterine inseminations are performed or sexual intercourse takes place.